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Regulation of Signal Duration and the Statistical Dynamics of Kinase Activation by Scaffold Proteins

Scaffolding proteins that direct the assembly of multiple kinases into a spatially localized signaling complex are often essential for the maintenance of an appropriate biological response. Although scaffolds are widely believed to have dramatic effects on the dynamics of signal propagation, the mec...

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Detalles Bibliográficos
Autores principales: Locasale, Jason W., Chakraborty, Arup K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2427176/
https://www.ncbi.nlm.nih.gov/pubmed/18584022
http://dx.doi.org/10.1371/journal.pcbi.1000099