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Activation of 5-HT(2A/C) Receptors Counteracts 5-HT(1A) Regulation of N-Methyl-D-aspartate Receptor Channels in Pyramidal Neurons of Prefrontal Cortex

Abnormal serotonin-glutamate interaction in prefrontal cortex (PFC) is implicated in the pathophysiology of many mental disorders, including schizophrenia and depression. However, the mechanisms by which this interaction occurs remain unclear. Our previous study has shown that activation of 5-HT(1A)...

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Detalles Bibliográficos
Autores principales: Yuen, Eunice Y., Jiang, Qian, Chen, Paul, Feng, Jian, Yan, Zhen
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2427346/
https://www.ncbi.nlm.nih.gov/pubmed/18442977
http://dx.doi.org/10.1074/jbc.M801713200