Polydactyly in the mouse mutant Doublefoot involves altered Gli3 processing and is caused by a large deletion in cis to Indian hedgehog

The mouse mutant Doublefoot (Dbf) shows preaxial polydactyly with 6–9 triphalangeal digits in all four limbs and additional abnormalities including a broadened skull, hydrocephalus, and a thickened, kinked tail. The autopod undergoes a characteristic expansion between late embryonic day (E) 10.5 and...

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Detalles Bibliográficos
Autores principales: Babbs, Christian, Furniss, Dominic, Morriss-Kay, Gillian M., Wilkie, Andrew O.M.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2428104/
https://www.ncbi.nlm.nih.gov/pubmed/18272352
http://dx.doi.org/10.1016/j.mod.2008.01.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2428104/
https://www.ncbi.nlm.nih.gov/pubmed/18272352
http://dx.doi.org/10.1016/j.mod.2008.01.001

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