Regulation of intestinal hPepT1 (SLC15A1) activity by phosphodiesterase inhibitors is via inhibition of NHE3 (SLC9A3)

The H(+)-coupled transporter hPepT1 (SLC15A1) mediates the transport of di/tripeptides and many orally-active drugs across the brush-border membrane of the small intestinal epithelium. Incubation of Caco-2 cell monolayers (15 min) with the dietary phosphodiesterase inhibitors caffeine and theophylli...

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Detalles Bibliográficos
Autores principales: Anderson, Catriona M.H., Thwaites, David T.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2428106/
https://www.ncbi.nlm.nih.gov/pubmed/17498647
http://dx.doi.org/10.1016/j.bbamem.2007.04.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2428106/
https://www.ncbi.nlm.nih.gov/pubmed/17498647
http://dx.doi.org/10.1016/j.bbamem.2007.04.006

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