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Epigenetic changes within the promoter region of the HLA-G gene in ovarian tumors

BACKGROUND: Previous findings have suggested that epigenetic-mediated HLA-G expression in tumor cells may be associated with resistance to host immunosurveillance. To explore the potential role of DNA methylation on HLA-G expression in ovarian cancer, we correlated differences in HLA-G expression wi...

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Detalles Bibliográficos
Autores principales: Menendez, Laura, Walker, L DeEtte, Matyunina, Lilya V, Totten, Kimberly A, Benigno, Benedict B, McDonald, John F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2429914/
https://www.ncbi.nlm.nih.gov/pubmed/18498645
http://dx.doi.org/10.1186/1476-4598-7-43