Decoding of Superimposed Traces Produced by Direct Sequencing of Heterozygous Indels

Direct Sanger sequencing of a diploid template containing a heterozygous insertion or deletion results in a difficult-to-interpret mixed trace formed by two allelic traces superimposed onto each other. Existing computational methods for deconvolution of such traces require knowledge of a reference s...

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Detalles Bibliográficos
Autores principales: Dmitriev, Dmitry A., Rakitov, Roman A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2429969/
https://www.ncbi.nlm.nih.gov/pubmed/18654614
http://dx.doi.org/10.1371/journal.pcbi.1000113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2429969/
https://www.ncbi.nlm.nih.gov/pubmed/18654614
http://dx.doi.org/10.1371/journal.pcbi.1000113

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