Engineering of a Genetically Encodable Fluorescent Voltage Sensor Exploiting Fast Ci-VSP Voltage-Sensing Movements

Ci-VSP contains a voltage-sensing domain (VSD) homologous to that of voltage-gated potassium channels. Using charge displacement (‘gating’ current) measurements we show that voltage-sensing movements of this VSD can occur within 1 ms in mammalian membranes. Our analysis lead to development of a gene...

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Detalles Bibliográficos
Autores principales: Lundby, Alicia, Mutoh, Hiroki, Dimitrov, Dimitar, Akemann, Walther, Knöpfel, Thomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2429971/
https://www.ncbi.nlm.nih.gov/pubmed/18575613
http://dx.doi.org/10.1371/journal.pone.0002514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2429971/
https://www.ncbi.nlm.nih.gov/pubmed/18575613
http://dx.doi.org/10.1371/journal.pone.0002514

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