Overexpression of a mutant form of TGFBI/BIGH3 induces retinal degeneration in transgenic mice

PURPOSE: Despite ubiquitous expression of the keratoepithelin (KE) protein encoded by the transforming growth factor beta induced/beta induced gene human clone 3 (TGFBI/BIGH3) gene, corneal dystrophies are restricted to the cornea, and no other tissues are affected. We investigated the role of TGFBI...

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Detalles Bibliográficos
Autores principales: Bustamante, Mauro, Tasinato, Andrea, Maurer, Fabienne, Elkochairi, Ilhem, Lepore, Mario G., Arsenijevic, Yvan, Pedrazzini, Thierry, Munier, Francis L., Schorderet, Daniel F.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2429980/
https://www.ncbi.nlm.nih.gov/pubmed/18568131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2429980/
https://www.ncbi.nlm.nih.gov/pubmed/18568131

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