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Circulating Precursor Levels of Endothelin-1 and Adrenomedullin, Two Endothelium-Derived, Counteracting Substances, in Sepsis

Plasma levels of endothelin-1 (ET-1) and adrenomedullin (ADM), two opposingly acting peptides, correlate with mortality in endotoxemia, but their measurement is cumbersome. New sandwich assays have been introduced that measure more stable precursor fragments. The objective of this study was to inves...

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Detalles Bibliográficos
Autores principales: Schuetz, Philipp, Christ-Crain, Mirjam, Morgenthaler, Nils G., Struck, Joachim, Bergmann, Andreas, Müller, Beat
Formato: Texto
Lenguaje:English
Publicado: Informa Healthcare 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430170/
https://www.ncbi.nlm.nih.gov/pubmed/18080871
http://dx.doi.org/10.1080/10623320701678326