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Src-family kinases in the development and therapy of Philadelphia chromosome-positive chronic myeloid leukemia and acute lymphoblastic leukemia
The BCR-ABL kinase inhibitor imatinib has shown significant efficacy in chronic myeloid leukemia (CML) and is the standard front-line therapy for patients in chronic phase. However, a substantial number of patients are either primarily refractory or acquire resistance to imatinib. While a number of...
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Formato: | Texto |
Lenguaje: | English |
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Informa Healthcare
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430171/ https://www.ncbi.nlm.nih.gov/pubmed/18203007 http://dx.doi.org/10.1080/10428190701713689 |