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Effects of acid antisecretory drugs on mucus barrier of the rat against 5-fluorouracil-induced gastrointestinal mucositis

OBJECTIVE: Acid antisecretory agents are used for the prophylaxis of cancer chemotherapy (CT)-induced gastrointestinal (GI) mucositis. Although these drugs seem to be clinically beneficial, data on their effects on the GI mucosal defense during CT treatment are scant. The objective of this study was...

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Detalles Bibliográficos
Autores principales: Saegusa, Yoichi, Ichikawa, Takafumi, Iwai, Tomohisa, Goso, Yukinobu, Ikezawa, Tomoaki, Nakano, Motoko, Shikama, Nobuaki, Saigenji, Katsunori, Ishihara, Kazuhiko
Formato: Texto
Lenguaje:English
Publicado: Informa Healthcare 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430178/
https://www.ncbi.nlm.nih.gov/pubmed/18415744
http://dx.doi.org/10.1080/00365520701811693