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HIV-1 Tat protein alter the tight junction integrity and function of retinal pigment epithelium: an in vitro study
BACKGROUND: How HIV-1 enter into the eyes remains obscure. We postulated that HIV-1 Tat protein can alter the expression of specific tight-junction proteins and disturb the blood retinal barrier, and contributes to HIV trafficking into the eyes. This study is to determine the effects of HIV-1 Tat pr...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430207/ https://www.ncbi.nlm.nih.gov/pubmed/18538010 http://dx.doi.org/10.1186/1471-2334-8-77 |