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Mechanism of Selenium-Induced Inhibition of Arsenic-Enhanced UVR Carcinogenesis in Mice

BACKGROUND: Hairless mice that ingested arsenite in drinking water exhibited more than a 5-fold enhancement of ultraviolet radiation (UVR) carcinogenesis, whereas arsenite alone was carcinogenically inactive. Dietary organoselenium blocked the cancer enhancement effect of arsenic but not cancer indu...

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Detalles Bibliográficos
Autores principales: Burns, Fredric J., Rossman, Toby, Vega, Katherine, Uddin, Ahmed, Vogt, Stefan, Lai, Barry, Reeder, Richard J.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430223/
https://www.ncbi.nlm.nih.gov/pubmed/18560523
http://dx.doi.org/10.1289/ehp.10978