Plasmodium vivax trophozoites insensitive to chloroquine

BACKGROUND: Plasmodium vivax is a major cause of malaria and is still primarily treated with chloroquine. Chloroquine inhibits the polymerization of haem to inert haemozoin. Free haem monomers are thought to catalyze oxidative damage to the Plasmodium spp. trophozoite, the stage when haemoglobin cat...

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Detalles Bibliográficos
Autores principales: Sharrock, Wesley W, Suwanarusk, Rossarin, Lek-Uthai, Usa, Edstein, Michael D, Kosaisavee, Varakorn, Travers, Thomas, Jaidee, Anchalee, Sriprawat, Kanlaya, Price, Ric N, Nosten, François, Russell, Bruce
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430579/
https://www.ncbi.nlm.nih.gov/pubmed/18505560
http://dx.doi.org/10.1186/1475-2875-7-94

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430579/
https://www.ncbi.nlm.nih.gov/pubmed/18505560
http://dx.doi.org/10.1186/1475-2875-7-94

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