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Plasmodium vivax trophozoites insensitive to chloroquine
BACKGROUND: Plasmodium vivax is a major cause of malaria and is still primarily treated with chloroquine. Chloroquine inhibits the polymerization of haem to inert haemozoin. Free haem monomers are thought to catalyze oxidative damage to the Plasmodium spp. trophozoite, the stage when haemoglobin cat...
Autores principales: | Sharrock, Wesley W, Suwanarusk, Rossarin, Lek-Uthai, Usa, Edstein, Michael D, Kosaisavee, Varakorn, Travers, Thomas, Jaidee, Anchalee, Sriprawat, Kanlaya, Price, Ric N, Nosten, François, Russell, Bruce |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430579/ https://www.ncbi.nlm.nih.gov/pubmed/18505560 http://dx.doi.org/10.1186/1475-2875-7-94 |
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