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Solution Structure and Sugar-Binding Mechanism of Mouse Latrophilin-1 RBL: a 7TM Receptor-Attached Lectin-Like Domain

Latrophilin-1 (Lat-1), a target receptor for α-Latrotoxin, is a putative G protein-coupled receptor implicated in synaptic function. The extracellular portion of Lat-1 contains a rhamnose binding lectin (RBL)-like domain of unknown structure. RBL domains, first isolated from the eggs of marine speci...

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Detalles Bibliográficos
Autores principales: Vakonakis, Ioannis, Langenhan, Tobias, Prömel, Simone, Russ, Andreas, Campbell, Iain D.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430599/
https://www.ncbi.nlm.nih.gov/pubmed/18547526
http://dx.doi.org/10.1016/j.str.2008.02.020