VEGF receptor antagonist Cyclo-VEGI reduces inflammatory reactivity and vascular leakiness and is neuroprotective against acute excitotoxic striatal insult

BACKGROUND: Excitotoxic brain insult is associated with extensive neuronal damage but could also cause inflammatory reactivity and vascular remodeling. The effects of the vascular endothelial growth factor (VEGF) inhibitor, Cyclo-VEGI on expression of VEGF, microgliosis and astrogliosis, blood-brain...

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Detalles Bibliográficos
Autores principales: Ryu, Jae K, McLarnon, James G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430697/
https://www.ncbi.nlm.nih.gov/pubmed/18492281
http://dx.doi.org/10.1186/1742-2094-5-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430697/
https://www.ncbi.nlm.nih.gov/pubmed/18492281
http://dx.doi.org/10.1186/1742-2094-5-18

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