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Identification of glycosaminoglycan binding regions in the Plasmodium falciparum encoded placental sequestration ligand, VAR2CSA

BACKGROUND: Pregnancy malaria is caused by Plasmodium falciparum-infected erythrocytes binding the placental receptor chondroitin sulfate A (CSA). This results in accumulation of parasites in the placenta with severe clinical consequences for the mother and her unborn child. Women become resistant t...

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Detalles Bibliográficos
Autores principales: Resende, Mafalda, Nielsen, Morten A, Dahlbäck, Madeleine, Ditlev, Sisse B, Andersen, Pernille, Sander, Adam F, Ndam, Nicaise T, Theander, Thor G, Salanti, Ali
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430714/
https://www.ncbi.nlm.nih.gov/pubmed/18534039
http://dx.doi.org/10.1186/1475-2875-7-104