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Identification of glycosaminoglycan binding regions in the Plasmodium falciparum encoded placental sequestration ligand, VAR2CSA
BACKGROUND: Pregnancy malaria is caused by Plasmodium falciparum-infected erythrocytes binding the placental receptor chondroitin sulfate A (CSA). This results in accumulation of parasites in the placenta with severe clinical consequences for the mother and her unborn child. Women become resistant t...
Autores principales: | Resende, Mafalda, Nielsen, Morten A, Dahlbäck, Madeleine, Ditlev, Sisse B, Andersen, Pernille, Sander, Adam F, Ndam, Nicaise T, Theander, Thor G, Salanti, Ali |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430714/ https://www.ncbi.nlm.nih.gov/pubmed/18534039 http://dx.doi.org/10.1186/1475-2875-7-104 |
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