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The Achilles Heel of the Trojan Horse Model of HIV-1 trans-Infection

To ensure their survival, microbial pathogens have evolved diverse strategies to subvert host immune defenses. The human retrovirus HIV-1 has been proposed to hijack the natural endocytic function of dendritic cells (DCs) to infect interacting CD4 T cells in a process termed trans-infection. Althoug...

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Detalles Bibliográficos
Autores principales: Cavrois, Marielle, Neidleman, Jason, Greene, Warner C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430767/
https://www.ncbi.nlm.nih.gov/pubmed/18584030
http://dx.doi.org/10.1371/journal.ppat.1000051