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The Achilles Heel of the Trojan Horse Model of HIV-1 trans-Infection
To ensure their survival, microbial pathogens have evolved diverse strategies to subvert host immune defenses. The human retrovirus HIV-1 has been proposed to hijack the natural endocytic function of dendritic cells (DCs) to infect interacting CD4 T cells in a process termed trans-infection. Althoug...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430767/ https://www.ncbi.nlm.nih.gov/pubmed/18584030 http://dx.doi.org/10.1371/journal.ppat.1000051 |