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Insights from mouse models into human retinoblastoma

Novel murine models of retinoblastoma based on Rb gene deletion in concert with inactivation of Rb family members have recently been developed. These new Rb knockout models of retinoblastoma provide excellent tools for pre-clinical studies and for the exploration of the genetics of tumorigenesis dri...

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Detalles Bibliográficos
Autor principal: MacPherson, David
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430952/
https://www.ncbi.nlm.nih.gov/pubmed/18489754
http://dx.doi.org/10.1186/1747-1028-3-9