Using the longest significance run to estimate region-specific p-values in genetic association mapping studies

BACKGROUND: Association testing is a powerful tool for identifying disease susceptibility genes underlying complex diseases. Technological advances have yielded a dramatic increase in the density of available genetic markers, necessitating an increase in the number of association tests required for...

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Detalles Bibliográficos
Autores principales: Lian, Ie-Bin, Lin, Yi-Hsien, Lin, Ying-Chao, Yang, Hsin-Chou, Chang, Chee-Jang, Fann, Cathy SJ
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430975/
https://www.ncbi.nlm.nih.gov/pubmed/18503718
http://dx.doi.org/10.1186/1471-2105-9-246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430975/
https://www.ncbi.nlm.nih.gov/pubmed/18503718
http://dx.doi.org/10.1186/1471-2105-9-246

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