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Destabilization of the Dystrophin-Glycoprotein Complex without Functional Deficits in α-Dystrobrevin Null Muscle
α-Dystrobrevin is a component of the dystrophin-glycoprotein complex (DGC) and is thought to have both structural and signaling roles in skeletal muscle. Mice deficient for α-dystrobrevin (adbn(−/−)) exhibit extensive myofiber degeneration and neuromuscular junction abnormalities. However, the bioch...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2432020/ https://www.ncbi.nlm.nih.gov/pubmed/18596960 http://dx.doi.org/10.1371/journal.pone.0002604 |