Binding to the Minor Groove of the Double-Strand, Tau Protein Prevents DNA from Damage by Peroxidation

Tau, an important microtubule associated protein, has been found to bind to DNA, and to be localized in the nuclei of both neurons and some non-neuronal cells. Here, using electrophoretic mobility shifting assay (EMSA) in the presence of DNA with different chain-lengths, we observed that tau protein...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Yan, Qu, Mei-Hua, Wang, Xing-Sheng, Chen, Lan, Wang, Dong-Liang, Liu, Ying, Hua, Qian, He, Rong-Qiao
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2432501/
https://www.ncbi.nlm.nih.gov/pubmed/18596978
http://dx.doi.org/10.1371/journal.pone.0002600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2432501/
https://www.ncbi.nlm.nih.gov/pubmed/18596978
http://dx.doi.org/10.1371/journal.pone.0002600

Ejemplares similares