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Binding to the Minor Groove of the Double-Strand, Tau Protein Prevents DNA from Damage by Peroxidation
Tau, an important microtubule associated protein, has been found to bind to DNA, and to be localized in the nuclei of both neurons and some non-neuronal cells. Here, using electrophoretic mobility shifting assay (EMSA) in the presence of DNA with different chain-lengths, we observed that tau protein...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2432501/ https://www.ncbi.nlm.nih.gov/pubmed/18596978 http://dx.doi.org/10.1371/journal.pone.0002600 |