Vaccinia Virus E3 Protein Prevents the Antiviral Action of ISG15

The ubiquitin-like modifier ISG15 is one of the most predominant proteins induced by type I interferons (IFN). In this study, murine embryo fibroblast (MEFs) and mice lacking the gene were used to demonstrate a novel role of ISG15 as a host defense molecule against vaccinia virus (VACV) infection. I...

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Detalles Bibliográficos
Autores principales: Guerra, Susana, Cáceres, Ana, Knobeloch, Klaus-Peter, Horak, Ivan, Esteban, Mariano
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2434199/
https://www.ncbi.nlm.nih.gov/pubmed/18604270
http://dx.doi.org/10.1371/journal.ppat.1000096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2434199/
https://www.ncbi.nlm.nih.gov/pubmed/18604270
http://dx.doi.org/10.1371/journal.ppat.1000096

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