FUS-DDIT3 Prevents the Development of Adipocytic Precursors in Liposarcoma by Repressing PPARγ and C/EBPα and Activating eIF4E

BACKGROUND: FUS-DDIT3 is a chimeric protein generated by the most common chromosomal translocation t(12;16)(q13;p11) linked to liposarcomas, which are characterized by the accumulation of early adipocytic precursors. Current studies indicate that FUS-DDIT3- liposarcoma develops from uncommitted prog...

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Detalles Bibliográficos
Autores principales: Pérez-Mancera, Pedro A., Bermejo-Rodríguez, Camino, Sánchez-Martín, Manuel, Abollo-Jiménez, Fernando, Pintado, Belén, Sánchez-García, Isidro
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2434200/
https://www.ncbi.nlm.nih.gov/pubmed/18596980
http://dx.doi.org/10.1371/journal.pone.0002569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2434200/
https://www.ncbi.nlm.nih.gov/pubmed/18596980
http://dx.doi.org/10.1371/journal.pone.0002569

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