APOBEC3G and APOBEC3F Require an Endogenous Cofactor to Block HIV-1 Replication

APOBEC3G (A3G)/APOBEC3F (A3F) are two members of APOBEC3 cytidine deaminase subfamily. Although they potently inhibit the replication of vif-deficient HIV-1, this mechanism is still poorly understood. Initially, A3G/A3F were thought to catalyze C-to-U transitions on the minus-strand viral cDNAs duri...

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Detalles Bibliográficos
Autores principales: Han, Yanxing, Wang, Xiaojun, Dang, Ying, Zheng, Yong-Hui
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435275/
https://www.ncbi.nlm.nih.gov/pubmed/18604271
http://dx.doi.org/10.1371/journal.ppat.1000095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435275/
https://www.ncbi.nlm.nih.gov/pubmed/18604271
http://dx.doi.org/10.1371/journal.ppat.1000095

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