Regulatory T cells inhibit Fas ligand-induced innate and adaptive tumour immunity

CD4(+)CD25(+) regulatory T cells (Treg) are known to influence T cell responses to tumours. Here we have explored the role of Treg in inhibiting not only adaptive, but also innate immune responses to tumours. To this end we used a Fas ligand (FasL)-expressing melanoma cell line in a mouse model. In...

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Detalles Bibliográficos
Autores principales: Simon, Anna Katharina, Jones, Emma, Richards, Hannah, Wright, Kate, Betts, Gareth, Godkin, Andrew, Screaton, Gavin, Gallimore, Awen
Formato: Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag GmbH 2007
Materias:
Immunomodulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435420/
https://www.ncbi.nlm.nih.gov/pubmed/17294404
http://dx.doi.org/10.1002/eji.200636593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435420/
https://www.ncbi.nlm.nih.gov/pubmed/17294404
http://dx.doi.org/10.1002/eji.200636593

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