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Regulatory T cells inhibit Fas ligand-induced innate and adaptive tumour immunity

CD4(+)CD25(+) regulatory T cells (Treg) are known to influence T cell responses to tumours. Here we have explored the role of Treg in inhibiting not only adaptive, but also innate immune responses to tumours. To this end we used a Fas ligand (FasL)-expressing melanoma cell line in a mouse model. In...

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Detalles Bibliográficos
Autores principales:	Simon, Anna Katharina, Jones, Emma, Richards, Hannah, Wright, Kate, Betts, Gareth, Godkin, Andrew, Screaton, Gavin, Gallimore, Awen
Formato:	Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag GmbH 2007
Materias:	Immunomodulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435420/ https://www.ncbi.nlm.nih.gov/pubmed/17294404 http://dx.doi.org/10.1002/eji.200636593

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