Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives

BACKGROUND: Lipid-soluble thiamine precursors have a much higher bioavailability than genuine thiamine and therefore are more suitable for therapeutic purposes. Benfotiamine (S-benzoylthiamine O-monophosphate), an amphiphilic S-acyl thiamine derivative, prevents the progression of diabetic complicat...

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Detalles Bibliográficos
Autores principales: Volvert, Marie-Laure, Seyen, Sandrine, Piette, Marie, Evrard, Brigitte, Gangolf, Marjorie, Plumier, Jean-Christophe, Bettendorff, Lucien
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435522/
https://www.ncbi.nlm.nih.gov/pubmed/18549472
http://dx.doi.org/10.1186/1471-2210-8-10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435522/
https://www.ncbi.nlm.nih.gov/pubmed/18549472
http://dx.doi.org/10.1186/1471-2210-8-10

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