Exploiting orthologue diversity for systematic detection of gain-of-function phenotypes

BACKGROUND: Systematic search for genes whose gain-of-function by exogenous expression confers an advantage in cell-based selective screenings is a powerful method for unbiased functional exploration of the genome, and has the potential to disclose new targets for cancer therapy. A major limit of th...

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Detalles Bibliográficos
Autores principales: Martelli, Maria Luisa, Isella, Claudio, Mira, Alessia, Fu, Limin, Cantarella, Daniela, Medico, Enzo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435555/
https://www.ncbi.nlm.nih.gov/pubmed/18510758
http://dx.doi.org/10.1186/1471-2164-9-254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435555/
https://www.ncbi.nlm.nih.gov/pubmed/18510758
http://dx.doi.org/10.1186/1471-2164-9-254

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