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Exploiting orthologue diversity for systematic detection of gain-of-function phenotypes
BACKGROUND: Systematic search for genes whose gain-of-function by exogenous expression confers an advantage in cell-based selective screenings is a powerful method for unbiased functional exploration of the genome, and has the potential to disclose new targets for cancer therapy. A major limit of th...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435555/ https://www.ncbi.nlm.nih.gov/pubmed/18510758 http://dx.doi.org/10.1186/1471-2164-9-254 |