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The Proto-Oncogene LRF Is under Post-Transcriptional Control of MiR-20a: Implications for Senescence

MicroRNAs (miRNAs) are short 20–22 nucleotide RNA molecules that act as negative regulators of gene expression via translational repression: they have been shown to play a role in development, proliferation, stress response, and apoptosis. The transcriptional regulator LRF (Leukemia/lymphoma Related...

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Detalles Bibliográficos
Autores principales: Poliseno, Laura, Pitto, Letizia, Simili, Marcella, Mariani, Laura, Riccardi, Luisa, Ciucci, Alessia, Rizzo, Milena, Evangelista, Monica, Mercatanti, Alberto, Pandolfi, Pier Paolo, Rainaldi, Giuseppe
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435600/
https://www.ncbi.nlm.nih.gov/pubmed/18596985
http://dx.doi.org/10.1371/journal.pone.0002542