Potentiation of Nerve Growth Factor-Induced Neurite Outgrowth by Fluvoxamine: Role of Sigma-1 Receptors, IP(3) Receptors and Cellular Signaling Pathways

BACKGROUND: Selective serotonin reuptake inhibitors (SSRIs) have been widely used and are a major therapeutic advance in psychopharmacology. However, their pharmacology is quite heterogeneous. The SSRI fluvoxamine, with sigma-1 receptor agonism, is shown to potentiate nerve-growth factor (NGF)-induc...

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Detalles Bibliográficos
Autores principales: Nishimura, Tomoko, Ishima, Tamaki, Iyo, Masaomi, Hashimoto, Kenji
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435603/
https://www.ncbi.nlm.nih.gov/pubmed/18596927
http://dx.doi.org/10.1371/journal.pone.0002558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435603/
https://www.ncbi.nlm.nih.gov/pubmed/18596927
http://dx.doi.org/10.1371/journal.pone.0002558

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