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Combined effects of 5-Fluorouracil, Folinic acid and Oxaliplatin on the expression of carcinoembryonic antigen in human colon cancer cells: pharmacological basis to develop an active antitumor immunochemotherapy

BACKGROUND: Five-fluorouracil (FU), mainly associated with leucovorin (L), plays an essential role in chemotherapy of colorectal carcinoma. Moreover, FU ± L has been found to increase the expression of tumor-associated carcinoembryonic antigen (CEA), that may be an important target in therapeutic pr...

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Detalles Bibliográficos
Autores principales: Prete, Salvatore P, Turriziani, Mario, Massara, Maria C, De Rossi, Alessia, Correale, Pierpaolo, De Vecchis, Liana, Torino, Francesco, Bonmassar, Laura, Aquino, Angelo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2438331/
https://www.ncbi.nlm.nih.gov/pubmed/18577244
http://dx.doi.org/10.1186/1756-9966-27-5