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Effect of Ras Inhibition in Hematopoiesis and BCR/ABL Leukemogenesis

Ras small GTPases are activated in many hematopoietic growth factor signaling and in hematological malignancies, but their role in hematopoiesis and leukemogenesis is not completely known. Here we examined the effect of Ras inhibition by a dominant negative mutant of Ras, N17 H-Ras, in adult hematop...

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Detalles Bibliográficos
Autores principales: Baum, Karina J, Ren, Ruibao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2438443/
https://www.ncbi.nlm.nih.gov/pubmed/18577264
http://dx.doi.org/10.1186/1756-8722-1-5