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Effect of Ras Inhibition in Hematopoiesis and BCR/ABL Leukemogenesis
Ras small GTPases are activated in many hematopoietic growth factor signaling and in hematological malignancies, but their role in hematopoiesis and leukemogenesis is not completely known. Here we examined the effect of Ras inhibition by a dominant negative mutant of Ras, N17 H-Ras, in adult hematop...
Autores principales: | Baum, Karina J, Ren, Ruibao |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2438443/ https://www.ncbi.nlm.nih.gov/pubmed/18577264 http://dx.doi.org/10.1186/1756-8722-1-5 |
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