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Identification and pharmacological characterization of the prostaglandin FP receptor and FP receptor variant complexes

Background and purpose: A prostamide analogue, bimatoprost, has been shown to be effective in reducing intraocular pressure, but its precise mechanism of action remains unclear. Hence, to elucidate the molecular mechanisms of this effect of bimatoprost, we focused on pharmacologically characterizing...

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Detalles Bibliográficos
Autores principales: Liang, Y, Woodward, D F, Guzman, V M, Li, C, Scott, D F, Wang, J W, Wheeler, L A, Garst, M E, Landsverk, K, Sachs, G, Krauss, A H-P, Cornell, C, Martos, J, Pettit, S, Fliri, H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440084/
https://www.ncbi.nlm.nih.gov/pubmed/18587449
http://dx.doi.org/10.1038/bjp.2008.142