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Identification and pharmacological characterization of the prostaglandin FP receptor and FP receptor variant complexes
Background and purpose: A prostamide analogue, bimatoprost, has been shown to be effective in reducing intraocular pressure, but its precise mechanism of action remains unclear. Hence, to elucidate the molecular mechanisms of this effect of bimatoprost, we focused on pharmacologically characterizing...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440084/ https://www.ncbi.nlm.nih.gov/pubmed/18587449 http://dx.doi.org/10.1038/bjp.2008.142 |