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Blockade of adenosine A(2B) receptors ameliorates murine colitis

BACKGROUND AND PURPOSE: The adenosine 2B (A(2B)) receptor is the predominant adenosine receptor expressed in the colon. Acting through the A(2B) receptor, adenosine mediates chloride secretion, as well as fibronectin and interleukin (IL)-6 synthesis and secretion in intestinal epithelial cells. A(2B...

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Detalles Bibliográficos
Autores principales: Kolachala, V L, Ruble, B K, Vijay-Kumar, M, Wang, L, Mwangi, S, Figler, H E, Figler, R A, Srinivasan, S, Gewirtz, A T, Linden, J, Merlin, D, Sitaraman, S V
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440087/
https://www.ncbi.nlm.nih.gov/pubmed/18536750
http://dx.doi.org/10.1038/bjp.2008.227