A Role for Polyploidy in the Tumorigenicity of Pim-1-Expressing Human Prostate and Mammary Epithelial Cells

BACKGROUND: Polyploidy is a prominent feature of many human cancers, and it has long been hypothesized that polyploidy may contribute to tumorigenesis by promoting genomic instability. In this study, we investigated whether polyploidy per se induced by a relevant oncogene can promote genomic instabi...

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Detalles Bibliográficos
Autores principales: Roh, Meejeon, Franco, Omar E., Hayward, Simon W., van der Meer, Riet, Abdulkadir, Sarki A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440349/
https://www.ncbi.nlm.nih.gov/pubmed/18596907
http://dx.doi.org/10.1371/journal.pone.0002572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440349/
https://www.ncbi.nlm.nih.gov/pubmed/18596907
http://dx.doi.org/10.1371/journal.pone.0002572

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