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Baseline Levels of Influenza-Specific CD4 Memory T-Cells Affect T-Cell Responses to Influenza Vaccines

BACKGROUND: Factors affecting immune responses to influenza vaccines have not been studied systematically. We hypothesized that T-cell and antibody responses to the vaccines are functions of pre-existing host immunity against influenza antigens. METHODOLOGY/PRINCIPAL FINDINGS: During the 2004 and 20...

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Detalles Bibliográficos
Autores principales: He, Xiao-Song, Holmes, Tyson H., Sasaki, Sanae, Jaimes, Maria C., Kemble, George W., Dekker, Cornelia L., Arvin, Ann M., Greenberg, Harry B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440350/
https://www.ncbi.nlm.nih.gov/pubmed/18596908
http://dx.doi.org/10.1371/journal.pone.0002574