Characterization of a Peptide Domain within the GB Virus C NS5A Phosphoprotein that Inhibits HIV Replication

BACKGROUND: GBV-C infection is associated with prolonged survival in HIV-infected people and GBV-C inhibits HIV replication in co-infection models. Expression of the GBV-C nonstructural phosphoprotein 5A (NS5A) decreases surface levels of the HIV co-receptor CXCR4, induces the release of SDF-1 and i...

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Detalles Bibliográficos
Autores principales: Xiang, Jinhua, McLinden, James H., Chang, Qing, Jordan, Emma L., Stapleton, Jack T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440355/
https://www.ncbi.nlm.nih.gov/pubmed/18596910
http://dx.doi.org/10.1371/journal.pone.0002580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440355/
https://www.ncbi.nlm.nih.gov/pubmed/18596910
http://dx.doi.org/10.1371/journal.pone.0002580

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