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Characterization of a Peptide Domain within the GB Virus C NS5A Phosphoprotein that Inhibits HIV Replication
BACKGROUND: GBV-C infection is associated with prolonged survival in HIV-infected people and GBV-C inhibits HIV replication in co-infection models. Expression of the GBV-C nonstructural phosphoprotein 5A (NS5A) decreases surface levels of the HIV co-receptor CXCR4, induces the release of SDF-1 and i...
Autores principales: | Xiang, Jinhua, McLinden, James H., Chang, Qing, Jordan, Emma L., Stapleton, Jack T. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440355/ https://www.ncbi.nlm.nih.gov/pubmed/18596910 http://dx.doi.org/10.1371/journal.pone.0002580 |
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