Immunological hotspots analyzed by docking simulations: evidence for a general mechanism in pemphigus vulgaris pathology and transformation

BACKGROUND: Pemphigus vulgaris (PV) is an acquired autoimmune blistering disorder in which greater than 80% of active patients produce autoantibodies to the desmosomal protein desmogelin 3 (Dsg3). As the disease progresses, 40–50% of patients may also develop reactivity to a second component of the...

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Detalles Bibliográficos
Autores principales: Tong, Joo Chuan, Sinha, Animesh A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440363/
https://www.ncbi.nlm.nih.gov/pubmed/18564435
http://dx.doi.org/10.1186/1471-2172-9-30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440363/
https://www.ncbi.nlm.nih.gov/pubmed/18564435
http://dx.doi.org/10.1186/1471-2172-9-30

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