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Warfarin dose and INR related to genotypes of CYP2C9 and VKORC1 in patients with myocardial infarction
BACKGROUND: Warfarin treatment has a narrow therapeutic range, requiring meticulous monitoring and dosage titration. Individual dosage requirement has recently partly been explained by genetic variation of the warfarin metabolizing enzyme CYP2C9 and the Vitamin K-activating enzyme VKORC1. In the WAR...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440373/ https://www.ncbi.nlm.nih.gov/pubmed/18559094 http://dx.doi.org/10.1186/1477-9560-6-7 |