Novel role for polycystin‐1 in modulating cell proliferation through calcium oscillations in kidney cells

Abstract.  Objectives: Polycystin‐1 (PC1), a signalling receptor regulating Ca(2+)‐permeable cation channels, is mutated in autosomal dominant polycystic kidney disease, which is typically characterized by increased cell proliferation. However, the precise mechanisms by which PC1 functions on Ca(2+)...

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Detalles Bibliográficos
Autores principales: Aguiari, G., Trimi, V., Bogo, M., Mangolini, A., Szabadkai, G., Pinton, P., Witzgall, R., Harris, P. C., Borea, P. A., Rizzuto, R., Del Senno, L.
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440503/
https://www.ncbi.nlm.nih.gov/pubmed/18422703
http://dx.doi.org/10.1111/j.1365-2184.2008.00529.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440503/
https://www.ncbi.nlm.nih.gov/pubmed/18422703
http://dx.doi.org/10.1111/j.1365-2184.2008.00529.x

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