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Novel role for polycystin‐1 in modulating cell proliferation through calcium oscillations in kidney cells
Abstract. Objectives: Polycystin‐1 (PC1), a signalling receptor regulating Ca(2+)‐permeable cation channels, is mutated in autosomal dominant polycystic kidney disease, which is typically characterized by increased cell proliferation. However, the precise mechanisms by which PC1 functions on Ca(2+)...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440503/ https://www.ncbi.nlm.nih.gov/pubmed/18422703 http://dx.doi.org/10.1111/j.1365-2184.2008.00529.x |