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The Pleiotropic Effects of Simvastatin on Retinal Microvascular Endothelium Has Important Implications for Ischaemic Retinopathies

BACKGROUND: Current guidelines encourage the use of statins to reduce the risk of cardiovascular disease in diabetic patients; however the impact of these drugs on diabetic retinopathy is not well defined. Moreover, pleiotropic effects of statins on the highly specialised retinal microvascular endot...

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Detalles Bibliográficos
Autores principales: Medina, Reinhold J., O'Neill, Christina L., Devine, Adrian B., Gardiner, Tom A., Stitt, Alan W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440506/
https://www.ncbi.nlm.nih.gov/pubmed/18612412
http://dx.doi.org/10.1371/journal.pone.0002584