Phase 1 Trial of Malaria Transmission Blocking Vaccine Candidates Pfs25 and Pvs25 Formulated with Montanide ISA 51

BACKGROUND: Pfs25 and Pvs25, surface proteins of mosquito stage of the malaria parasites P. falciparum and P. vivax, respectively, are leading candidates for vaccines preventing malaria transmission by mosquitoes. This single blinded, dose escalating, controlled Phase 1 study assessed the safety and...

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Detalles Bibliográficos
Autores principales: Wu, Yimin, Ellis, Ruth D., Shaffer, Donna, Fontes, Erica, Malkin, Elissa M., Mahanty, Siddhartha, Fay, Michael P., Narum, David, Rausch, Kelly, Miles, Aaron P., Aebig, Joan, Orcutt, Andrew, Muratova, Olga, Song, Guanhong, Lambert, Lynn, Zhu, Daming, Miura, Kazutoyo, Long, Carole, Saul, Allan, Miller, Louis H., Durbin, Anna P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440546/
https://www.ncbi.nlm.nih.gov/pubmed/18612426
http://dx.doi.org/10.1371/journal.pone.0002636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440546/
https://www.ncbi.nlm.nih.gov/pubmed/18612426
http://dx.doi.org/10.1371/journal.pone.0002636

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